| Self-measured (blood pressure) arterial stiffness index: A promising new measure of arterial stiffness. | |
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MedLine Citation:
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PMID: 20409865 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Increased arterial stiffness is predictive of increased cardiovascular risk. The ambulatory arterial stiffness index is a new measure derived from 24-hour ambulatory blood pressure (BP) monitoring. We retrospectively studied 59 consecutive patients, (36 females; age 62 +/- 12 years), evaluated for hypertension in an academic cardiology practice. All had eight or more self-measured BP recorded over a period of 2 through 8 weeks while stable. The self-measured arterial stiffness index (SMASI) was calculated according to the same formula as the ambulatory arterial stiffness index, 1 minus the regression slope of the regression line of diastolic plotted against systolic BP. Mean SMASI was 62 +/- 0.20. SMASI correlated directly with age (r = 0.27; P = .03), BP load (r = 0.40; P = .002), home pulse pressure (r = 0.47; P < .001), and office pulse pressure (r = 0.44; P = .001). SMASI was higher in patients with multiple cardiovascular risk factors and correlated with pulse wave velocity (r = 0.45; P = .04) among 21 patients who underwent arterial tonometry. SMASI correlated with left ventricle (LV) mass/body surface area (BSA) (r = 0.30; P = .035) in 50 patients. SMASI increases with age, is associated with weaker BP control, hypertensive organ damage and correlates with pulse wave velocity. SMASI obtained by self-measured BP may serve as a useful surrogate measure of arterial stiffness. |
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Authors:
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Ghazanfar Qureshi; Jason M Lazar; Hera Javaid; Michael Weber; Louis Salciccioli |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Society of Hypertension : JASH Volume: 1 ISSN: 1933-1711 ISO Abbreviation: J Am Soc Hypertens Publication Date: 2007 Sep-Oct |
Date Detail:
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Created Date: 2010-04-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101312518 Medline TA: J Am Soc Hypertens Country: United States |
Other Details:
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Languages: eng Pagination: 347-52 Citation Subset: - |
Affiliation:
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Division of Cardiovascular Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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