Document Detail

Self-expanding endovascular stent in experimental atherosclerosis. Work in progress.
MedLine Citation:
PMID:  2916030     Owner:  NLM     Status:  MEDLINE    
To investigate the physiologic and histologic responses induced by the self-expanding endovascular prosthesis, rabbits subjected to a combination of high-cholesterol diet and intravascular trauma underwent stent implantation. The results were compared with those obtained with the placement of stents in the healthy aortas of rabbits. Stents in healthy aortic tissue led to stent intimalization, previously reported in canine studies. For stents placed in animals subjected to a high-cholesterol diet but no intimal trauma, it was found that the stent was not the source of atherogenesis. Stents placed in atheromatous plaque were found to radially compress plaque with time and to stimulate for formation of a fibrotic crust. The results suggest that the self-expanding stent protects against progressive encroachment of the vessel lumen by atherosclerotic tissue.
H Rousseau; F Joffre; C Raillat; M Julian; M T Pierragi; F Chalabi; H Bouissou
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  170     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-03-23     Completed Date:  1989-03-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  773-8     Citation Subset:  AIM; IM    
Department of Radiology, University of Rangueil, Toulouse, France.
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MeSH Terms
Aorta, Abdominal / pathology
Arteriosclerosis / pathology,  surgery*
Blood Vessel Prosthesis*
Cholesterol, Dietary / administration & dosage
Constriction, Pathologic / pathology
Microscopy, Electron
Prosthesis Design
Reg. No./Substance:
0/Cholesterol, Dietary

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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