Document Detail


Self-reported medication adherence and symptom experience in adults with HIV.
MedLine Citation:
PMID:  21377900     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Symptom burden has been identified as a predictor of medication adherence, but little is known about which symptoms are most strongly implicated. This study examines self-reported medical adherence in relation to demographic, clinical, and symptom characteristics among 302 adults living with HIV. Only 12% reported missing medication during the 3-day assessment, but 75% gave at least one reason for missing it in the previous month. Poor adherence was associated with higher viral load and greater symptom burden. Trouble sleeping and difficulty concentrating were strongly associated with poor adherence. Given that "forgetting" was the most common reason for missing medication and nearly one third reported sleeping through dose time, future research should examine the influence of sleep disturbance on adherence. Effective management of common symptoms, such as sleep disturbance, fatigue, and gastrointestinal side-effects of medications may result in better adherence, as well as improved clinical outcomes and quality of life.
Authors:
Caryl Gay; Carmen J Portillo; Ryan Kelly; Traci Coggins; Harvey Davis; Bradley E Aouizerat; Clive R Pullinger; Kathryn A Lee
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2011-03-05
Journal Detail:
Title:  The Journal of the Association of Nurses in AIDS Care : JANAC     Volume:  22     ISSN:  1552-6917     ISO Abbreviation:  J Assoc Nurses AIDS Care     Publication Date:    2011 Jul-Aug
Date Detail:
Created Date:  2011-06-17     Completed Date:  2011-10-13     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  9111870     Medline TA:  J Assoc Nurses AIDS Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  257-68     Citation Subset:  IM; N; X    
Copyright Information:
Copyright © 2011 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
HIV Infections / drug therapy*,  physiopathology
Humans
Male
Patient Compliance*
Self Disclosure*
Grant Support
ID/Acronym/Agency:
1 UL RR024131/RR/NCRR NIH HHS; 5 R01MH074358/MH/NIMH NIH HHS; 5P20MD0005444/MD/NIMHD NIH HHS; KL2 RR024130/RR/NCRR NIH HHS; R01 MH074358/MH/NIMH NIH HHS; R01 MH074358-04/MH/NIMH NIH HHS
Comments/Corrections

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