Document Detail


Self-medication with antibiotics in Europe: a case for action.
MedLine Citation:
PMID:  20615180     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Unlike most other drugs that only affect individual patients if used incorrectly for self-medication, misused antibiotics add to the global risk of increased spread of bacterial resistance. This review focuses on self-medication with antibiotics in Europe and its determinants. High prevalence of self-medication with antibiotics has been repeatedly found in Southern and Eastern European countries that also report high levels of antibiotic resistance. Despite being illegal, over the counter dispensation of systemic antibiotics occurs in several European Union Member States. A second major source of self-medication is the availability of "leftover" antibiotics which results from either patient non-compliance or dispensation of a larger number of tablets than needed for one single course. The potentially modifiable factors associated with self-medication are: availability of antibiotics without prescription, pack-based antibiotic dispensing system, misconceptions of the general public about the efficacy of antibiotics for minor illnesses and prescribing of antibiotics for minor ailments by physicians. Measures that may reduce and prevent self-medication include dispensation of exact tablet quantities in pharmacies as already implemented e.g. in the UK, Netherlands, the Czech Republic and the United States, and enforcement of existing laws prohibiting over-the-counter sales of antibiotics. Such measures should be embedded in a general policy to change the culture of antibiotic use by improving awareness of the general public and professionals about antibiotics and the risks associated with their use as well as reducing misconceptions about the need for antibiotics for minor ailments.
Authors:
Larissa Grigoryan; Dominique L Monnet; Flora M Haaijer-Ruskamp; Marc J M Bonten; Stålsby Lundborg; Theo J M Verheij
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current drug safety     Volume:  5     ISSN:  1574-8863     ISO Abbreviation:  Curr Drug Saf     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-07     Completed Date:  2011-01-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101270895     Medline TA:  Curr Drug Saf     Country:  United Arab Emirates    
Other Details:
Languages:  eng     Pagination:  329-32     Citation Subset:  IM    
Affiliation:
Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands. larissa_holland@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / administration & dosage,  therapeutic use*
Drug Resistance, Microbial
Drug Utilization / statistics & numerical data
Europe / epidemiology
Health Knowledge, Attitudes, Practice
Humans
Patient Compliance
Patient Education as Topic
Prevalence
Public Health
Self Medication*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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