| Selenoamino acids in tissues of rats administered inorganic selenium. | |
| | |
MedLine Citation:
|
PMID: 1250164 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
There are conflicting reports in the literature concerning the synthesis of selenoamino acids from inorganic selenium in animals, and this work was undertaken to further investigate this. Pronase digests of acetone powders of liver and kidney tissue from rats administered 75SeO3= were subjected to fractionation by cation exchange chromatography using current methods for separating the various amino acids. Very little, if any, selenocystine was found in the digests. However, good evidence was obtained for the occurrence of 2,7-diamino-4-thia-5-selenaoctanedioic acid. It is suggested that the selenocysteine portion of this compound was formed by the reduction of the selenite to selenide with its subsequent incorporation into the amino acid by the action of serine hydrolase (E C 4.2.1.22). No selenomethionine was found under the conditions of this study. |
| | |
Authors:
|
O E Olson; I S Palmer |
Related Documents
:
|
12062414 - Phytanic acid, but not pristanic acid, mediates the positive effects of phytol derivati... 17322064 - Combined effects of rosiglitazone and conjugated linoleic acid on adiposity, insulin se... 26704 - Gamma-glutamyl transpeptidase in lactating mammary secretory tissue of cow and rat. 7396484 - Development of bacterial spoilage at adipose tissue surfaces of fresh meat. 12169314 - Cryptoporic and isocryptoporic acids from the fungal cultures of polyporus arcularius a... 22214994 - First prokaryotic biodiversity assessment using molecular techniques of an acidic river... |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
|
Title: Metabolism: clinical and experimental Volume: 25 ISSN: 0026-0495 ISO Abbreviation: Metab. Clin. Exp. Publication Date: 1976 Mar |
Date Detail:
|
Created Date: 1976-04-19 Completed Date: 1976-04-19 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0375267 Medline TA: Metabolism Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 299-306 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amino Acids, Sulfur
/
biosynthesis* Animals Cysteine / analogs & derivatives, biosynthesis Cystine / analogs & derivatives, biosynthesis Kidney / metabolism Liver / metabolism Male Oxidation-Reduction Radioisotopes Rats Selenium / pharmacology* |
| Chemical | |
Reg. No./Substance:
|
0/Amino Acids, Sulfur; 0/Radioisotopes; 52-90-4/Cysteine; 56-89-3/Cystine; 7782-49-2/Selenium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dietary protein intake and dynamic aspects of whole body nitrogen metabolism in adult humans.
Next Document: Myocardial infarction in the familial forms of hypertriglyceridemia.