Document Detail

Selenium supplementation improves mood in a double-blind crossover trial.
MedLine Citation:
PMID:  2096413     Owner:  NLM     Status:  MEDLINE    
The possibility that a sub-clinical deficiency of the trace element selenium might exist in a sample of the British population was examined by giving a selenium supplemented for 5 weeks. Using a double-blind crossover design 50 subjects received either a placebo or 100 micrograms selenium on a daily basis. On three occasions they filled in the Profile of Moods state. Mood did not change when taking the placebo, whereas when taking the selenium the subjects reported a substantial improvement after both 2.5 and 5 weeks.
D Benton; R Cook
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Psychopharmacology     Volume:  102     ISSN:  0033-3158     ISO Abbreviation:  Psychopharmacology (Berl.)     Publication Date:  1990  
Date Detail:
Created Date:  1991-07-17     Completed Date:  1991-07-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7608025     Medline TA:  Psychopharmacology (Berl)     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  549-50     Citation Subset:  IM    
Department of Psychology, University College, Swansea, Wales, UK.
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MeSH Terms
Affect / drug effects*
Double-Blind Method
Middle Aged
Selenium / pharmacology*
Reg. No./Substance:

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