Document Detail


Selenium status of very low birth weight infants.
MedLine Citation:
PMID:  8134169     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The selenium (Se) intake and status of 82 very low birth weight infants (birth weight 1110 +/- 286 g, gestational age 29.2 +/- 3 wk, mean +/- SD) was assessed at 36.3 +/- 3 postconceptional wk, at 40.1 +/- 4 wk (hospital discharge), and at 3, 6, 9, and 12 +/- 0.75 mo corrected for gestational age. Infants were fed formula containing 0.13 mumol/L (10 micrograms/L) Se. Se-dependent glutathione peroxidase activity in red blood cells declined corresponding to low Se intakes (micrograms/kd/d) for the first 6 mo. With increased consumption of solid foods, intakes of dietary Se and Se-dependent glutathione peroxidase activity increased at 9 mo, suggesting that the earlier supply of Se was suboptimal. Se-dependent glutathione peroxidase activity and intakes of Se were lower in males than in females (p < 0.05). We suggest that infant formulas should probably contain 0.26-0.33 mumol/L (20-25 micrograms/L) Se, particularly those formulas consumed by very low birth weight infants.
Authors:
J K Friel; W L Andrews; D R Long; M R L'Abbé
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Pediatric research     Volume:  34     ISSN:  0031-3998     ISO Abbreviation:  Pediatr. Res.     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1994-04-18     Completed Date:  1994-04-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0100714     Medline TA:  Pediatr Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  293-6     Citation Subset:  IM    
Affiliation:
Department of Biochemistry, Memorial University of Newfoundland, St. John's, Canada.
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MeSH Terms
Descriptor/Qualifier:
Erythrocytes / enzymology*
Female
Gestational Age
Glutathione Peroxidase / blood*
Humans
Infant Food* / analysis,  standards
Infant, Low Birth Weight / blood*
Infant, Newborn
Infant, Premature / blood*
Male
Nutritional Requirements
Prospective Studies
Selenium / administration & dosage,  deficiency*
Chemical
Reg. No./Substance:
7782-49-2/Selenium; EC 1.11.1.9/Glutathione Peroxidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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