| Selenium in global food systems. | |
| | |
MedLine Citation:
|
PMID: 11348568 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Food systems need to produce enough of the essential trace element Se to provide regular adult intakes of at least 40 microg/d to support the maximal expression of the Se enzymes, and perhaps as much as 300 microg/d to reduce risks of cancer. Deprivation of Se is associated with impairments in antioxidant protection, redox regulation and energy production as consequences of suboptimal expression of one or more of the Se-containing enzymes. These impairments may not cause deficiency signs in the classical sense, but instead contribute to health problems caused by physiological and environmental oxidative stresses and infections. At the same time, supranutritional intakes of Se, i.e. intakes greater than those required for selenocysteine enzyme expression, appear to reduce cancer risk. The lower, nutritional, level is greater than the typical intakes of many people in several parts of the world, and few populations have intakes approaching the latter, supranutritional, level. Accordingly, low Se status is likely to contribute to morbidity and mortality due to infectious as well as chronic diseases, and increasing Se intakes in all parts of the world can be expected to reduce cancer rates. |
| | |
Authors:
|
G F Combs |
Related Documents
:
|
12362778 - Methylseleno-amino acid content of food materials by stable isotope dilution mass spect... 6928958 - The ability of foods to stain two composite resins. 12615418 - Comparative bioavailability of selenium to aquatic organisms after biological treatment... 15141878 - Identification and concentration of soy phytoestrogens in commercial dog foods. 6698168 - Cadmium in foods and the diet. 15092388 - Survival, growth and reproduction of daphnia carinata (crustacea: cladocera) exposed to... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: The British journal of nutrition Volume: 85 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 2001 May |
Date Detail:
|
Created Date: 2001-05-11 Completed Date: 2001-06-07 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
|
Languages: eng Pagination: 517-47 Citation Subset: IM |
Affiliation:
|
Department of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA. gfc2@cornell.edu. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Biological Availability Cardiomyopathies / etiology, prevention & control Cartilage Diseases / etiology Diet Dietary Supplements Food Supply Humans Neoplasms / prevention & control Nutritional Physiological Phenomena* Nutritional Status Selenium* / administration & dosage, deficiency, metabolism Soil World Health* |
| Chemical | |
Reg. No./Substance:
|
0/Soil; 7782-49-2/Selenium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A European carotenoid database to assess carotenoid intakes and its use in a five-country comparativ...
Next Document: Magnesium deficiency improves glucose homeostasis in the rat: studies in vivo and in isolated islets...