| Selenium bioavailability from naturally produced high-selenium peas and oats in selenium-deficient rats. | |
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MedLine Citation:
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PMID: 21553810 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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We determined the bioavailability of selenium (Se) from yellow peas and oats harvested from high-Se soil of South Dakota, United States. The Se concentration was 13.5 ± 0.2 and 2.5 ± 0.1 mg/kg (dry weight) for peas and oats, respectively. Male weanling Sprague-Dawley rats were depleted of Se by feeding them a 30% Torula yeast-based diet (4.1 µg Se/kg) for 56 days, and then they were replenished with Se for an additional 50 days by feeding them the same diet supplemented with 20, 30 or 40 µg Se/kg from peas or oats, respectively. Selenium bioavailability was determined on the basis of the restoration of Se-dependent enzyme activities and tissue Se concentrations in Se-depleted rats, comparing those responses for yellow peas and oats to those for L-selenomethionine (SeMet; used as a reference) by using a slope-ratio method. Dietary supplementation with peas or oats resulted in linear or log-linear, dose-dependent increases in glutathione peroxidase activities in blood and liver and in thioredoxin reductase activity in liver. Supplementation with the peas or oats resulted in linear or log-linear, dose-dependent increases in Se concentrations of plasma, liver, gastrocnemius muscle and kidneys. The overall bioavailability was approximately 88% for Se from yellow peas and 92% from oats, compared to SeMet. We conclude that Se from naturally produced high-Se yellow peas or oats is highly bioavailable in this model and these high-Se foods may be a good dietary source of Se. |
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Authors:
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Lin Yan; Luann K Johnson |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-5-9 |
Journal Detail:
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Title: Journal of agricultural and food chemistry Volume: - ISSN: 1520-5118 ISO Abbreviation: - Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-5-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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