Document Detail

Selective venous sampling in recurrent and persistent hyperparathyroidism: indication, technique, and results.
MedLine Citation:
PMID:  15573246     Owner:  NLM     Status:  MEDLINE    
Between 1992 and 2002, 542 patients underwent a surgical treatment for hyperparathyroidism in our department. Twenty-three selective venous sampling procedures (SVS) were performed because of the failure of the other methods of diagnosis. These patients have recurrent or persistent hyperparathyroidism. Noninvasive methods of topographical diagnosis have failed or they have given contradictory results. In our experience, the surgeon needs a precise localization of the pathological glands in these difficult cases. In our series of SVS, specificity was 85.7% and sensitivity was 94.7%. Our results show that a high postoperative gradient of parathyroid hormone in the internal thoracic veins indicates an ectopic pathological gland in the thymus. A high gradient in a vertebral vein indicates a pathological superior parathyroid gland, usually in a retro-esophageal position.
Philippe C J Chaffanjon; David Voirin; Ashok Vasdev; Olivier Chabre; Norman M Kenyon; Pierre Yves Brichon
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Publication Detail:
Type:  Journal Article     Date:  2004-09-29
Journal Detail:
Title:  World journal of surgery     Volume:  28     ISSN:  0364-2313     ISO Abbreviation:  World J Surg     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-12-01     Completed Date:  2005-02-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7704052     Medline TA:  World J Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  958-61     Citation Subset:  IM    
Service de Chirurgie Générale et Thoracique, CHU de Grenoble, BP217, 38043, Grenoble Cedex 09, France.
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MeSH Terms
Blood Specimen Collection / methods*
Hyperparathyroidism / diagnosis*,  surgery
Middle Aged
Parathyroid Glands / abnormalities
Sensitivity and Specificity

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