Document Detail


Selective transformations of organic compounds by imidozirconocene complexes.
MedLine Citation:
PMID:  12469354     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Imidozirconocene complexes (Cp(2)Zr=NR(THF)) possess a rich reaction chemistry, in contrast to many imido complexes of later transition metals. The synthesis and structural characteristics of these compounds are briefly described, along with a qualitative molecular orbital description of the metallocene-imido interaction. Imidozirconocene complexes react at the Zr=N linkage with a variety of X-H bonds, and undergo overall [2 + 2] cycloaddition reactions with a wide range of unsaturated organic and organometallic compounds. Results of studies detailing the scope and mechanism of these reactions are presented herein, along with applications to catalytic hydroamination, imine metathesis, and asymmetric transformations.
Authors:
Andrew P Duncan; Robert G Bergman
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Chemical record (New York, N.Y.)     Volume:  2     ISSN:  1527-8999     ISO Abbreviation:  Chem Rec     Publication Date:  2002  
Date Detail:
Created Date:  2002-12-06     Completed Date:  2004-07-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  101085550     Medline TA:  Chem Rec     Country:  United States    
Other Details:
Languages:  eng     Pagination:  431-45     Citation Subset:  IM    
Copyright Information:
Copyright 2002 The Japan Chemical Journal Forum and Wiley Periodicals, Inc.
Affiliation:
Department of Chemistry, University of Californa, Berkley, California 94720, USA.
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MeSH Terms
Descriptor/Qualifier:
Alkenes / chemistry
Alkynes / chemistry
Azides / chemistry
Catalysis
Imines / chemistry*
Molecular Conformation
Molecular Structure
Nitrogen / chemistry
Organic Chemicals / chemical synthesis*,  chemistry*
Organometallic Compounds / chemistry*
Zirconium / chemistry*
gamma-Aminobutyric Acid / chemistry
Grant Support
ID/Acronym/Agency:
GM-25459/GM/NIGMS NIH HHS; R01 GM025459-24/GM/NIGMS NIH HHS
Chemical
Reg. No./Substance:
0/Alkenes; 0/Alkynes; 0/Azides; 0/Imines; 0/Organic Chemicals; 0/Organometallic Compounds; 1291-32-3/Zirconocene dichloride; 56-12-2/gamma-Aminobutyric Acid; 7440-67-7/Zirconium; 7727-37-9/Nitrogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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