Document Detail


Selective termination and elective reduction in twin pregnancies: 10 years experience at a single centre.
MedLine Citation:
PMID:  9756315     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Selective termination is employed in multifetal pregnancies, in the presence of an abnormal fetus, in order to improve the prognosis of the normal fetuses. The term elective reduction is used to describe reduction in twin pregnancies for maternal medical conditions, psychological, or socioeconomic reasons. The purpose of this study was to evaluate the factors that influence outcome in such pregnancies. Eighty-two twin pregnancies underwent selective termination (n = 59) or elective reduction (n = 23) over a 10-year period. Early procedures, performed < or = 14 weeks (n = 31), had a pregnancy loss of 9.7% and a mean procedure-to-loss interval of 4.1 +/- 2.8 weeks; mean birthweight was 3299 +/- 395 g in survivors, with a mean gestational age at delivery of 38.4 +/- 2.3 weeks. In comparison, procedures performed > 14 weeks (n = 51) had a pregnancy loss of 7.8%, with a procedure-to-loss interval of 1.2 +/- 0.6 weeks. Mean birthweight was 2577 +/- 999 g, with a mean gestational age at delivery of 35.7 +/- 5 weeks. In conclusion, outcomes were more favourable among patients who underwent a first trimester procedure. The slight increase in pregnancy loss may be attributed to a higher than expected rate of spontaneous abortions in the first trimester, as manifested by the higher procedure-to-loss interval after a first trimester procedure. These facts underscore the importance of early detection of fetal abnormalities in twin pregnancies by ultrasonography and chorionic villus sampling.
Authors:
Y Yaron; K D Johnson; P K Bryant-Greenwood; R L Kramer; M P Johnson; M I Evans
Related Documents :
23090465 - Vbac: what does the evidence show?
3931835 - High incidence of preterm births and early losses in pregnancy after in vitro fertilisa...
23210535 - The impact of vitamin d in pregnancy on extraskeletal health in children: a systematic ...
6493665 - Triplet pregnancy with second trimester abortion and delivery of twins at 35 weeks' ges...
11074085 - Birth order and left-handedness revisited: some recent findings in chimpanzees (pan tro...
47785 - An error in rh testing in pregnancy.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  13     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-12-17     Completed Date:  1998-12-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2301-4     Citation Subset:  IM    
Affiliation:
Center for Fetal Diagnosis and Therapy, Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, MI, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Abortion, Spontaneous / etiology
Adult
Birth Weight
Congenital Abnormalities / diagnosis
Diseases in Twins / diagnosis
Ethics, Medical
Female
Fertilization in Vitro
Gestational Age
Humans
Michigan
Oocyte Donation
Ovulation Induction
Pregnancy
Pregnancy Outcome
Pregnancy Reduction, Multifetal* / adverse effects,  methods
Pregnancy Trimester, First
Pregnancy Trimester, Second
Pregnancy, Multiple*
Prenatal Diagnosis
Twins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Stress and anxiety do not result in pregnancy wastage.
Next Document:  Evaluation of serum inhibin A as a surveillance marker after conservative management of tubal pregna...