| Selective termination: clinical experience and residual risks. | |
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MedLine Citation:
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PMID: 2360590 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Assisted reproductive technologies have aided thousands of couples, but complications have resulted in multifetal pregnancies creating a bitter irony for infertility patients. In an effort to increase the rate of intact survival, we have successfully performed transabdominal first-trimester selective termination procedures on 22 pregnancies including one octuplet, five quintuplet, twelve quadruplet, and four triplet gestations. There have been eight sets of twins, and two singletons delivered, seven twin pregnancies are ongoing, and one early and four late losses of pregnancies. With experience we now counsel as to a high likelihood of a technically successful procedure, but we still have concerns for late losses. We have tried to balance the arguments about the direct harms of performing selective termination and the obstetric risks of not performing selective termination. We believe that selective termination should not be considered a "social" procedure. Our data do not yet make clear whether one, two, or three is the optimal number of embryos to leave. Therefore, on the basis of both current obstetric risk factors and ethical reasoning we will continue to support our protocol of optimally leaving twins. |
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Authors:
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M I Evans; M May; A Drugan; J C Fletcher; M P Johnson; R J Sokol |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 162 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1990 Jun |
Date Detail:
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Created Date: 1990-08-02 Completed Date: 1990-08-02 Revised Date: 2004-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1568-72; discussion 1572-5 Citation Subset: AIM; E; IM |
Affiliation:
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Division of Reproductive Genetics, Hutzel Hospital-Wayne State University, Detroit, MI 48201. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Induced
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methods* Ethics, Medical Female Fertilization in Vitro Fetal Death / etiology Gamete Intrafallopian Transfer Humans Ovulation Induction Pregnancy Pregnancy, Multiple* Pregnant Women Risk Assessment* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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