Document Detail

Selective reduction and termination of multiple pregnancies.
MedLine Citation:
PMID:  20863776     Owner:  NLM     Status:  MEDLINE    
The substantial increase in high order multiple pregnancies in the last two decades as a result of assisted reproductive techniques has necessitated the development of multifetal pregnancy reduction as a management tool to decrease fetal number and improve perinatal survival. The evidence in favour of reduction in pregnancies with more than four fetuses to twins is undisputed. Despite the recent improvements in expectant management of triplets with reasonable perinatal outcomes, the evidence suggests that reduction to twins significantly reduces the risk of preterm delivery without an increase in miscarriage rates. Recent advances in vascular-occlusive techniques have allowed the possibility of selective termination in monochorionic pregnancies in the presence of discordant anomalies or indeed multifetal reduction in non-trichorionic triplets, with radiofrequency ablation and cord occlusion appearing to be the most successful. However, the techniques vary in complexity and complication rates, which increase with gestation. Hence the need to refer these pregnancies early to specialist centres.
R C Wimalasundera
Related Documents :
7799976 - Multifetal pregnancy: risks and methods of reduction.
714326 - Bromocriptine. clinical experience in the induction of pregnancy in amenorrhea-galactor...
9408866 - Terbutaline pump tocolysis in high-order multiple gestation.
7102766 - Management of multifetal pregnancies: sixteen years' experience at the sloan hospital f...
8860106 - Increase in prostaglandin bioavailability precedes the onset of human parturition.
12056756 - Sem examination of the dorsal lingual papillae of pregnant rats.
Publication Detail:
Type:  Journal Article; Review     Date:  2010-09-22
Journal Detail:
Title:  Seminars in fetal & neonatal medicine     Volume:  15     ISSN:  1878-0946     ISO Abbreviation:  Semin Fetal Neonatal Med     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-10-18     Completed Date:  2011-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101240003     Medline TA:  Semin Fetal Neonatal Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  327-35     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ltd. All rights reserved.
Centre for Fetal Care, Queen Charlotte's & Chelsea Hospital, Imperial College Healthcare Trust, Du Cane Road, London W12 0HS, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Catheter Ablation
Decision Making
Embolization, Therapeutic
Gestational Age
Laser Coagulation
Pregnancy Outcome
Pregnancy Reduction, Multifetal / adverse effects,  methods*
Twins, Monozygotic

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  [Immature ovarian tumour and dilated myocardiopathy].
Next Document:  Acute grade III and IV acromioclavicular dislocations: outcomes and pitfalls of reconstruction proce...