Document Detail


Selective maintenance of recombination between the sex chromosomes.
MedLine Citation:
PMID:  24529284     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A hallmark of many sex chromosomes is the dramatically reduced rate of recombination between them in the heterogametic sex (e.g. between the X and Y). Sexually antagonistic selection is thought to be the main selective driver of this reduced recombination, with tighter linkage strengthening the association between alleles favourable to females and the X, as well as alleles favourable to males and the Y. Nevertheless, many sex chromosomes retain substantial levels of recombination over millions of years, and some old sex chromosomes remain homomorphic with few signs of recombination suppression and the chromosomal degradation expected to follow. This paper explores the selective factors that can maintain recombination between the sex chromosomes. Specifically, by analysing the dynamics of genes that modify the rate of recombination, I present results demonstrating that certain forms of selection - all involving overdominance in males - can positively maintain recombination in the pseudo-autosomal region. To understand these cases, one has to revise our standard view of sexual antagonistic selection as involving two partners (males and females) to three partners (the X in females, the X in males and the Y).
Authors:
S P Otto
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-2-15
Journal Detail:
Title:  Journal of evolutionary biology     Volume:  -     ISSN:  1420-9101     ISO Abbreviation:  J. Evol. Biol.     Publication Date:  2014 Feb 
Date Detail:
Created Date:  2014-2-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8809954     Medline TA:  J Evol Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2014 The Author. Journal of Evolutionary Biology © 2014 European Society For Evolutionary Biology.
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