Document Detail

Selective laser trabeculoplasty for intraocular pressure elevation after intravitreal triamcinolone acetonide injection.
MedLine Citation:
PMID:  16840867     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Intravitreal injection of triamcinolone acetonide has increasingly become a therapeutic option for neovascular, inflammatory, and edematous intraocular diseases. A common side effect of this treatment is a steroid-induced elevation of intraocular pressure. In most of these patients, the rise in intraocular pressure can be treated topically. Those cases that cannot be treated medically have been treated with filtering surgery. This report presents a case of intraocular pressure elevation after intravitreal triamcinolone acetonide injection that was successfully treated with selective laser trabeculoplasty. CASE REPORT: A 63-year-old white man presented with brow ache on the right side approximately 3 months after undergoing intravitreal injection of triamcinolone acetonide for diabetic macular edema in the right eye. Applanation tonometry revealed an intraocular pressure of 45 mm Hg in the involved eye. After initial treatment with topical medications, the patient underwent selective laser trabeculoplasty. Now, 6 months postlaser treatment, the intraocular pressure in the involved eye is stable at 15 mm Hg without topical medications. CONCLUSIONS: A steroid-induced elevation of intraocular pressure is a common and widely reported side effect of treatment with intravitreal triamcinolone acetonide. This case report suggests that selective laser trabeculoplasty has potential as first- or second-line therapy for intraocular pressure elevation after intravitreal triamcinolone acetonide injection.
Joseph J Pizzimenti; Maritza M Nickerson; Claire E Pizzimenti; Ann G Kasten-Aker
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Optometry and vision science : official publication of the American Academy of Optometry     Volume:  83     ISSN:  1040-5488     ISO Abbreviation:  Optom Vis Sci     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-14     Completed Date:  2006-08-22     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8904931     Medline TA:  Optom Vis Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  421-5     Citation Subset:  IM    
Nova Southeastern University, College of Optometry, Ft. Lauderdale, Florida 33328-2018, USA.
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MeSH Terms
Diabetic Retinopathy / complications
Follow-Up Studies
Glucocorticoids / administration & dosage,  adverse effects*
Intraocular Pressure / drug effects
Laser Therapy*
Macular Edema / drug therapy,  etiology
Middle Aged
Ocular Hypertension / chemically induced,  physiopathology,  surgery*
Trabeculectomy / methods*
Triamcinolone Acetonide / administration & dosage,  adverse effects*
Vitreous Body
Reg. No./Substance:
0/Glucocorticoids; 76-25-5/Triamcinolone Acetonide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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