Document Detail


Selective injection of iopentol, iohexol and metrizoate into the left coronary artery of the dog. Induction of ventricular fibrillation and decrease of aortic pressure.
MedLine Citation:
PMID:  2980315     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In twenty beagle dogs selective injections were made into the left coronary artery with iopentol, iohexol and metrizoate in doses of 4 ml, 8 ml and 16 ml. Thirty-six iopentol injections, 35 iohexol injections and 37 metrizoate injections were made. Frequencies of ventricular fibrillation were significantly lower (p less than 0.05) after iopentol (0%) and iohexol (3%) than after metrizoate (22%). Iopentol and iohexol also produced significantly less decrease in aortic blood pressure than metrizoate at the different doses.
Authors:
T Almén; L Bååth
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta radiologica. Supplementum     Volume:  370     ISSN:  0365-5954     ISO Abbreviation:  Acta Radiol Suppl     Publication Date:  1987  
Date Detail:
Created Date:  1992-04-24     Completed Date:  1992-04-24     Revised Date:  2008-04-09    
Medline Journal Info:
Nlm Unique ID:  0370370     Medline TA:  Acta Radiol Suppl     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  65-8     Citation Subset:  IM    
Affiliation:
Department of Diagnostic Radiology, Malmö Allmänna Sjukhus, University of Lund, Sweden.
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MeSH Terms
Descriptor/Qualifier:
Animals
Aorta / physiology*
Blood Pressure / drug effects*
Contrast Media / administration & dosage,  adverse effects*
Coronary Angiography*
Dogs
Electrocardiography / drug effects
Female
Injections
Iohexol / administration & dosage,  adverse effects,  diagnostic use
Male
Metrizoate / administration & dosage,  adverse effects,  diagnostic use
Triiodobenzoic Acids / administration & dosage,  adverse effects,  diagnostic use
Ventricular Fibrillation / chemically induced*
Chemical
Reg. No./Substance:
0/Contrast Media; 0/Triiodobenzoic Acids; 1949-45-7/Metrizoate; 66108-95-0/Iohexol; 89797-00-2/iopentol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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