Document Detail

Selective immunoglobulin M deficiency presenting with recurrent impetigo: a case report and review of the literature.
MedLine Citation:
PMID:  19218822     Owner:  NLM     Status:  MEDLINE    
Selective immunoglobulin M (IgM) deficiency is a rare disorder defined by a decreased serum level of IgM and normal levels of other immunoglobulin classes. The disease has not been well described and the cause remains unknown. Patients with IgM deficiency may present with a wide spectrum of clinical manifestations, from asymptomatic to life-threatening infections, including recurrent respiratory and gastrointestinal infections, allergy and autoimmunity. Here, we report a 6.5-year-old otherwise healthy boy with selective IgM deficiency who presented with multiple recurrent impetigo. We reviewed the published data regarding selective deficiency of IgM.
Tugba Belgemen; Emine Suskan; Figen Dogu; Aydan Ikinciogullari
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-02-12
Journal Detail:
Title:  International archives of allergy and immunology     Volume:  149     ISSN:  1423-0097     ISO Abbreviation:  Int. Arch. Allergy Immunol.     Publication Date:  2009  
Date Detail:
Created Date:  2009-06-12     Completed Date:  2009-07-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211652     Medline TA:  Int Arch Allergy Immunol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  283-8     Citation Subset:  IM    
Department of Pediatrics, Pediatric Emergency and Outpatient Unit, Ankara University School of Medicine, Ankara, Turkey.
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MeSH Terms
Amoxicillin / therapeutic use
Anti-Bacterial Agents / therapeutic use
Clavulanic Acid / therapeutic use
Dysgammaglobulinemia / complications,  diagnosis*,  drug therapy
Immunoglobulin M / blood,  deficiency*
Impetigo / immunology*
Lymphocyte Subsets / immunology*,  microbiology
Mupirocin / therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Immunoglobulin M; 12650-69-0/Mupirocin; 26787-78-0/Amoxicillin; 58001-44-8/Clavulanic Acid

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