Document Detail


Selective hypoplasia of pelvic bone marrow.
MedLine Citation:
PMID:  7444370     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
6 patients with thrombocytopenia and anaemia had fatty marrow replacement at the site of an iliac crest. 52Fe scans showed marked abnormalities of bone marrow distribution. Particularly, the uptake of radioiron into the pelvis was almost absent. The sternal marrow was cellular. Studies of the bone marrow which included cytology, histology and electron microscopy failed to reveal why the pelvic marrow was aplastic. Occasional vascular lesions could not seen in the iliac crest bone marrow sections. The cellular morphology showed slight maturation abnormalities. Ferrokinetics were consistent with erythroid marrow hypoplasia. The pelvic and sternal marrow cellularity in patients with pancytopenia may not be representative of the cellularity of the whole marrow, and the pelvic marrow especially may be prone to aplasia.
Authors:
A Ferrant; J Rodhain; A Cordier; M Symann; J L Michaux; G Sokal
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of haematology     Volume:  25     ISSN:  0036-553X     ISO Abbreviation:  Scand J Haematol     Publication Date:  1980 Jul 
Date Detail:
Created Date:  1981-02-24     Completed Date:  1981-02-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404507     Medline TA:  Scand J Haematol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  12-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Anemia, Aplastic / pathology*
Blood Cell Count
Bone Marrow / pathology*
Colony-Forming Units Assay
Erythropoiesis
Female
Humans
Ilium / pathology
Iron / metabolism
Iron Radioisotopes / diagnostic use
Male
Middle Aged
Sternum / cytology
Thrombocytopenia / pathology*
Chemical
Reg. No./Substance:
0/Iron Radioisotopes; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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