Document Detail


Selective destruction of a host blood cell type by a parasitoid wasp.
MedLine Citation:
PMID:  6435126     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Foreign objects that enter the hemocoel of Drosophila melanogaster larvae are encapsulated by one type of blood cell, the lamellocyte, yet eggs of the parasitoid wasp Leptopilina heterotoma remain unencapsulated in D. melanogaster larval hosts that have many lamellocytes. Here we demonstrate that shortly after a female wasp oviposits in the hemocoel the lamellocytes undergo morphological changes and lose their adhesiveness. These affected blood cells are eventually destroyed as the parasitoid egg continues its development. The factor responsible for lamellocyte destruction, lamellolysin, is contained in an accessory gland of the female reproductive system and is injected along with the egg into the host hemocoel. Lamellolysin does not alter the morphology or the defense functions of the other types of blood cells in the host.
Authors:
R M Rizki; T M Rizki
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Proceedings of the National Academy of Sciences of the United States of America     Volume:  81     ISSN:  0027-8424     ISO Abbreviation:  Proc. Natl. Acad. Sci. U.S.A.     Publication Date:  1984 Oct 
Date Detail:
Created Date:  1984-11-19     Completed Date:  1984-11-19     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7505876     Medline TA:  Proc Natl Acad Sci U S A     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  6154-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Drosophila melanogaster / immunology*
Escherichia coli
Female
Hemolymph / immunology
Hymenoptera / parasitology*
Larva / immunology
Mutation
Ovum / immunology
Phagocytosis
Temperature
Wasps / parasitology*
Grant Support
ID/Acronym/Agency:
AG-01945/AG/NIA NIH HHS
Comments/Corrections

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