Document Detail

Selective cardiac hypothermia versus coronary perfusion. A study of ischemic complications in two series of 100 consecutive valvular patients.
MedLine Citation:
PMID:  1150730     Owner:  NLM     Status:  MEDLINE    
Myocardial protection, in two parallel series of 100 consecutive valvular patients operated upon between June 1972 and July 1973 in Broussais Hospital, was afforded in two different ways: one withh hypothermic ischemia (H.I.) as it was advocated by N. Shumway, the other with coronary perfusion (C.P.) of a beating heart with consecutive ischemic periods limited to 20 minutes. Three parameters were used to evaluate the quality of protection: death with primary cardiogenic shock, post-operative myocardial infarction and acute cardiac insufficiency making it necessary to use post-operative inotropic support. Death was 1% (H.I.) and 5% (C.P.). Infarctions were 5% (H.I.) and 8% (C.P.). Acute cardiac insufficiency was: with cardiogenic shock 0% (H.I.) and 4% (C.P.), without cardiogenic shock 8% (H.I.) and 2% (C.P.). Peculiar aspects of myocardial infarction in each series are analyzed, and apparent absence of correlation between aortic cross-clamp time and ischemic complications is discussed. A "myocardial intrinsic factor" seems to be part of each valvular group and appears also to be an important factor in producing ischemic complications.
M Bercot; A Deloche; A Piwnica; A Carpentier; C Dubost
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of cardiovascular surgery     Volume:  16     ISSN:  0021-9509     ISO Abbreviation:  J Cardiovasc Surg (Torino)     Publication Date:    1975 May-Jun
Date Detail:
Created Date:  1975-11-06     Completed Date:  1975-11-06     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0066127     Medline TA:  J Cardiovasc Surg (Torino)     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  232-40     Citation Subset:  IM    
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MeSH Terms
Age Factors
Aortic Valve
Cardiac Volume
Cardiopulmonary Bypass
Coronary Disease / etiology*
Extracorporeal Circulation* / methods
Heart Valve Diseases / surgery*
Hypothermia, Induced* / methods
Middle Aged
Mitral Valve
Myocardial Infarction / etiology
Postoperative Complications / etiology
Regression Analysis
Shock, Cardiogenic / etiology,  mortality
Time Factors
Tricuspid Valve

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