Document Detail

Selective birth in a dyzygotic twin pregnancy with discordancy for Down's syndrome.
MedLine Citation:
PMID:  2535009     Owner:  NLM     Status:  MEDLINE    
The discovery of a twin pregnancy by ultrasound at the intake procedure for chorionic villus sampling or amniocentesis is not unusual because of the raised incidence of dizygotic twins at increased maternal age. Since the conception of dizygotic twins is genetically a separate and unrelated event, the risk of abnormalities in each twin is independent, but additive. In advanced maternal age, the risk of chromosomal aneuploidy in one of both fetuses varies between 2 and 6% [1]. This case report discusses the early prenatal diagnosis of twins discordant for Down's syndrome.
L Pijpers; M G Jahoda; A Reuss; E S Sachs; F J Los; J W Wladimiroff
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Fetal therapy     Volume:  4     ISSN:  0257-2788     ISO Abbreviation:  Fetal Ther     Publication Date:  1989  
Date Detail:
Created Date:  1990-12-05     Completed Date:  1990-12-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8700083     Medline TA:  Fetal Ther     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  58-60     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Hospital Rotterdam-Dijkzigt Erasmus University, The Netherlands.
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MeSH Terms
Abortion, Eugenic
Down Syndrome / diagnosis*
Pregnancy, Multiple*
Twins, Dizygotic*

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