| Selective synthesis of either isoindole- or isoindoline-1-carboxylic acid esters by Pd(0)-catalyzed enolate arylation. | |
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MedLine Citation:
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PMID: 20738127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two efficient palladium-catalyzed intramolecular α-arylation reactions of α-amino acid esters have been developed that allow either 1-isoindolecarboxylic acid esters or the corresponding isoindolines to be selectively synthesized simply by a slight change of reaction conditions. |
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Authors:
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Daniel Solé; Olga Serrano |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of organic chemistry Volume: 75 ISSN: 1520-6904 ISO Abbreviation: J. Org. Chem. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-10 Completed Date: 2011-01-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985193R Medline TA: J Org Chem Country: United States |
Other Details:
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Languages: eng Pagination: 6267-70 Citation Subset: IM |
Affiliation:
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Laboratori de Química Orgànica, Facultat de Farmàcia, and Institut de Biomedicina, Universitat de Barcelona, 08028 Barcelona, Spain. dsole@ub.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Amino Acids
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chemistry* Carboxylic Acids / chemical synthesis*, chemistry Catalysis Cyclization Esters / chemical synthesis*, chemistry* Isoindoles / chemical synthesis*, chemistry Molecular Structure Palladium / chemistry* Stereoisomerism |
| Chemical | |
Reg. No./Substance:
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0/Amino Acids; 0/Carboxylic Acids; 0/Esters; 0/Isoindoles; 7440-05-3/Palladium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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