Document Detail

Selective Soil Particle Adherence to Hands: Implications for Understanding Oral Exposure to Soil Contaminants.
MedLine Citation:
PMID:  23148503     Owner:  NLM     Status:  Publisher    
Over the last 30 years, there has been extensive research designed to quantify the extent of oral bioavailability and bioaccessibility of organic and inorganic contaminants in soil. One aspect of this research is the soil particle size selected to represent environmental exposures, which may affect study results and comparability across studies. Different research groups have studied soil particle sizes ranging from <45 μm to <2000 μm. This article reviews the historical and technical considerations that pertain to the selection of an appropriate particle size fraction for evaluating the relative oral bioavailability of chemicals from soil, which include (1) how the resultant data will be used in human health risk assessment, (2) soil fractions historically used in oral bioavailability studies, (3) studies of soil adherence to human hands, (4) the distribution of contaminants in soils as a function of particle size, and (5) the effect of differential bioavailability as a function of soil particle size and geochemical matrix. These factors are first discussed from a general perspective, applicable to all contaminants in soil, and then more specifically for polycyclic aromatic hydrocarbons (PAHs) in soil. Based on this review, a specific soil particle size of <150 μm is recommended for future studies on the oral bioavailability and bioaccessibility of PAHs in soil.
Michael V Ruby; Yvette W Lowney
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-14
Journal Detail:
Title:  Environmental science & technology     Volume:  -     ISSN:  1520-5851     ISO Abbreviation:  Environ. Sci. Technol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0213155     Medline TA:  Environ Sci Technol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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