Document Detail

Selective PEEP in acute bilateral lung disease. Effect on patients in the lateral posture.
MedLine Citation:
PMID:  6356754     Owner:  NLM     Status:  MEDLINE    
Seven patients with acute respiratory failure due to diffuse and fairly uniform lung disease were studied during mechanical ventilation in the lateral decubital position with: (a) zero end-expiratory pressure (ZEEP) through a double-lumen oro-bronchial tube to permit a recording of the ventilation to each lung; (b) bilateral positive end-expiratory pressure (PEEP) of 1.2 kPa, with maintenance of ventilation distribution between lungs as observed during ZEEP; (c) selective PEEP of 1.2 kPa, applied to the dependent lung only, with ventilation as during ZEEP; and (d) conventional PEEP of 1.2 kPa applied to both lungs through a single-lumen tube, with free distribution of ventilation between the lungs. During ZEEP, 69% of ventilation was distributed to the non-dependent and 31% to the dependent lung; cardiac output was 6.51 X min-1, venous admixture (QS/QT) 40% and arterial oxygen tension (PaO2) 8.3 kPa. With bilateral PEEP, functional residual capacity (FRC) increased by 0.331, cardiac output was reduced to 5.11 X min-1 and venous admixture to 32%. PaO2 increased to 10.1 kPa. With selective PEEP the dependent lung FRC increased by 0.211 and the FRC of the non-dependent lung decreased by 0.081. Cardiac output increased to 6.11 X min-1, which was no longer significantly different from that during ZEEP. Venous admixture remained at the same level as with bilateral PEEP.(ABSTRACT TRUNCATED AT 250 WORDS)
S Baehrendtz; L Bindslev; G Hedenstierna; J Santesson
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta anaesthesiologica Scandinavica     Volume:  27     ISSN:  0001-5172     ISO Abbreviation:  Acta Anaesthesiol Scand     Publication Date:  1983 Aug 
Date Detail:
Created Date:  1983-12-17     Completed Date:  1983-12-17     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370270     Medline TA:  Acta Anaesthesiol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  311-7     Citation Subset:  IM    
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MeSH Terms
Airway Resistance
Blood Gas Analysis
Cardiac Output
Evaluation Studies as Topic
Lung Diseases / physiopathology,  therapy*
Middle Aged
Oxygen / blood
Positive-Pressure Respiration*
Pulmonary Circulation
Respiration, Artificial
Reg. No./Substance:

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