| Selective esterifications of primary alcohols in a water-containing solvent. | |
| | |
MedLine Citation:
|
PMID: 22937741 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Oxyma and an oxyma derivative, (2,2-dimethyl-1,3-dioxolan-4-yl)methyl 2-cyano-2-(hydroxyimino)acetate (5b), displayed a remarkable effect on selective esterifications of primary alcohols. A wide range of carboxylic acids could be esterified with primary alcohols by using EDCI, NaHCO(3), and Oxyma or Oxyma derivative 5b in 5% H(2)O-CH(3)CN. Oxyma derivative 5b is particularly useful, since it could be removed after the reaction via a simple basic or an acidic aqueous workup procedure. |
| | |
Authors:
|
Yong Wang; Bilal A Aleiwi; Qinghui Wang; Michio Kurosu |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2012-08-31 |
Journal Detail:
|
Title: Organic letters Volume: 14 ISSN: 1523-7052 ISO Abbreviation: Org. Lett. Publication Date: 2012 Sep |
Date Detail:
|
Created Date: 2012-09-21 Completed Date: 2013-01-11 Revised Date: 2013-04-16 |
Medline Journal Info:
|
Nlm Unique ID: 100890393 Medline TA: Org Lett Country: United States |
Other Details:
|
Languages: eng Pagination: 4910-3 Citation Subset: IM |
Affiliation:
|
Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 881 Madison Avenue, Memphis, Tennessee 38163-0001, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acetates
/
chemistry* Alcohols / chemistry* Esterification Molecular Structure Oximes / chemistry* Solvents Water / chemistry* |
| Grant Support | |
ID/Acronym/Agency:
|
AI AI084411/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Acetates; 0/Alcohols; 0/Oximes; 0/Solvents; 0/ethyl 2-cyano-2-(hydroxyimino)acetate; 7732-18-5/Water |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Multiple biomarker tissue arrays: A computational approach to identifying protein-protein interactio...
Next Document: Development of Antioxidant Packaging Material by Applying Corn-Zein to LLDPE Film in Combination wit...