Document Detail

Selected zinc metabolism parameters and left ventricle mass in echocardiographic examination in primary arterial hypertension.
MedLine Citation:
PMID:  17873356     Owner:  NLM     Status:  MEDLINE    
The basal systolic and diastolic blood pressure, body mass index, left ventricular mass, serum and lymphocyte zinc levels, serum aldosterone, plasma rennin and angiotensin-converting enzyme activities, sodium and potassium levels, and the total and ouabain-dependent rate constants of zinc efflux from lymphocytes were measured in a group of 41 individuals of both sexes (overall age 46.3 +/- 11.4 years), of which 18 were women (48.5 +/- 7.1 years old) and 23 were men (44.7 +/- 13.8 years old). There were no significant differences between these parameters while dividing the subjects into groups according to sex, despite differences in weight, left ventricle mass, plasma rennin activity, and serum aldosterone content. Only the total and ouabain-dependent rate constants of zinc efflux from lymphocytes slightly negatively correlated to left ventricular mass, r = -0.30 to r = -0.36. This may constitute indirect evidence of zinc deficiency in cardiomyocytes of some hypertensive individuals with left ventricular hypertrophy.
Sławomir Tubek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biological trace element research     Volume:  118     ISSN:  0163-4984     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-09-17     Completed Date:  2007-12-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  138-45     Citation Subset:  IM    
Faculty of Physical Education and Physiotherapy, Institute of Technology, Opole, Prószkowska Street 76, Opole, Poland.
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MeSH Terms
Blood Pressure
Body Mass Index
Heart Ventricles* / anatomy & histology,  ultrasonography
Hypertension* / metabolism,  pathology
Lymphocytes / metabolism
Middle Aged
Zinc / metabolism*
Reg. No./Substance:

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