Document Detail


Selected zinc metabolism parameters in women with arterial hypotension.
MedLine Citation:
PMID:  17634629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the present study, differences between selected zinc parameters in healthy women and arterial hypotension patients were compared. The patients had baseline systolic blood pressure that did not surpass 100 mm Hg. During the orthostatic test, a decrease of over 20 mm Hg was seen and the patients reported dizziness, limpness, and palpitations. The patients had higher levels of lymphocyte zinc than those of the controls and exhibited a positive correlation between serum zinc and the ouabain-dependent zinc efflux from lymphocytes (r = 0.49), and, in turn, this efflux was negatively correlated to the serum aldosterone level (r = -0.35). Except for the differences in their systolic blood pressure and lymphocyte zinc, none of the tested zinc metabolism parameters showed significant differences between the patients and the controls. As in arterial hypertension, the obtained results indicate that zinc plays a significant role in regulation of arterial blood pressure.
Authors:
Sławomir Tubek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biological trace element research     Volume:  116     ISSN:  0163-4984     ISO Abbreviation:  Biol Trace Elem Res     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-07-19     Completed Date:  2007-09-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911509     Medline TA:  Biol Trace Elem Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  73-9     Citation Subset:  IM    
Affiliation:
Faculty of Physical Education and Physiotherapy, Institute of Technology, Opole, and Clinic of Cardiology, Medical Academy, Wrocław, Prószkowska Street 76, 45-758 Opole, Poland.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aldosterone / metabolism
Arteries / pathology*
Blood Pressure
Disease Susceptibility
Female
Humans
Hydrogen-Ion Concentration
Hypotension / blood*
Lymphocytes / metabolism
Renin / blood
Zinc / analysis,  blood,  deficiency,  metabolism*
Chemical
Reg. No./Substance:
52-39-1/Aldosterone; 7440-66-6/Zinc; EC 3.4.23.15/Renin

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