Document Detail


Selected echocardiographic variables change more rapidly in dogs that die from myxomatous mitral valve disease.
MedLine Citation:
PMID:  22366569     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: To determine if echocardiographic measurements change at a greater rate in dogs with myxomatous mitral valve disease (MMVD) that die of cardiac mortality. ANIMALS: Client-owned dogs (n = 242) with MMVD of varying severity were recruited from first opinion private practice. Only dogs which died during the study period (n = 102) were included in statistical analyses. METHODS: Prospective cohort study comparing the rate of change of echocardiographic variables between dogs that experienced cardiac mortality and those that experienced non-cardiac mortality. Measurements were repeated approximately every 6 months and repeated measures linear models were constructed to estimate the rate of change of each variable over time. RESULTS: Left ventricular (LV) end-diastolic diameter, normalized for body weight (LVEDDN) increased over time in both mortality groups. LV end-systolic diameter, normalized for body weight (LVESDN), LV end-diastolic diameter to LV free wall thickness in diastole (LVEDD/LVFWd) ratio, E wave velocity, E- to A-wave velocity ratio and left atrial to aortic root diameter ratio all increased over time in the cardiac mortality group, but did not change in the non-cardiac mortality group. MR velocity decreased over time in the cardiac mortality group but did not change in the non-cardiac mortality group. Tricuspid regurgitation jet velocity increased over time in both mortality groups. A wave velocity and fractional shortening did not change over time in either mortality group. CONCLUSIONS: Serial echocardiographic examination every 6-12 months is useful to identify dogs with progressive MMVD that are at increased risk of cardiac mortality.
Authors:
Melanie J Hezzell; Adrian Boswood; Walasinee Moonarmart; Jonathan Elliott
Related Documents :
15347709 - Pet for evaluation of differential myocardial perfusion dynamics after vegf gene therap...
15053189 - Coronary revascularization in ischemic cardiomyopathy.
6334199 - Timing of coronary revascularization after acute myocardial infarction. early and late ...
15064079 - An echocardiogram-based 16-segment model for predicting left ventricular ejection fract...
15226929 - Coronary artery revascularization: reoperations performed on 124 consecutive patients.
23799879 - Association of subclinical myocardial injury with arterial stiffness in patients with t...
21742089 - A multicenter, randomized, controlled study of mechanical left ventricular unloading wi...
1111559 - Echoventriculographic detection, localization, and quantification of left ventricular a...
6700209 - Etiology of atrioventricular-conduction abnormalities following cardiac surgery.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-24
Journal Detail:
Title:  Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology     Volume:  -     ISSN:  1875-0834     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101163270     Medline TA:  J Vet Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier B.V. All rights reserved.
Affiliation:
The Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prediction of first onset of congestive heart failure in dogs with degenerative mitral valve disease...
Next Document:  Ultrasonographic measurement of flow-mediated vasodilation in dogs with chronic valvular disease.