| Seizures in the neonatal intensive care unit of the 1980s. Types, Etiologies, Timing. | |
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MedLine Citation:
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PMID: 3342595 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A retrospective review was taken of 150 newborns with seizures evaluated at the same medical center and by the same investigator(s) from 1982 to 1987. The aims of the study were to determine in this current population the distribution of clinical seizure types, the distribution of causative etiologies, and the relation of etiology to the timing of onset of the seizures. Seizures were classified as subtle, multifocal clonic, generalized tonic, focal clonic, and myoclonic. Subtle (65% of total) and multifocal clonic seizures (54% of total) were the most common seizure types. Subtle seizures usually occurred in combination with other seizure types. Only one seizure type was related to gestational age, i.e., focal clonic seizures in the term infant. Hypoxic-ischemic encephalopathy (65% of total) was by far the most common etiology in both preterm and term infants. Seizures with hypoxic-ischemic encephalopathy occurred characteristically early in the neonatal period, i.e., 90 percent in the first 2 days of life. Moreover, 80 percent of all seizures in the first 2 days of life were related to hypoxic-ischemic encephalopathy. |
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Authors:
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G Calciolari; J M Perlman; J J Volpe |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical pediatrics Volume: 27 ISSN: 0009-9228 ISO Abbreviation: Clin Pediatr (Phila) Publication Date: 1988 Mar |
Date Detail:
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Created Date: 1988-04-05 Completed Date: 1988-04-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372606 Medline TA: Clin Pediatr (Phila) Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 119-23 Citation Subset: AIM; IM |
Affiliation:
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Department of Pediatrics, Washington University School of Medicine, Children's Hospital, St. Louis, MO 63110. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cerebral Hemorrhage
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complications Cerebrovascular Disorders / complications Epilepsy / complications, drug therapy Female Gestational Age Humans Infant, Low Birth Weight Infant, Newborn Infant, Premature, Diseases / etiology Intensive Care Units, Neonatal Male Phenobarbital / therapeutic use Retrospective Studies Seizures / classification, etiology* |
| Chemical | |
Reg. No./Substance:
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50-06-6/Phenobarbital |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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