| Seizures in Chiari I malformation: a clinical and electroencephalographic study. | |
| | |
MedLine Citation:
|
PMID: 10573467 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Seven subjects with Chiari I malformations and seizures (four males, three females; age range 11 years, 7 months to 36 years; mean, 22.28 +/- 7.58 years; median, 21) were identified in four different centers from among a group of 10 patients. Our aim was to analyze clinical and electroencephalographic characteristics of seizures in this etiologically homogeneous group of patients. Most of the seizures were of the complex partial type, and paroxysmal abnormalities were mainly localized over the frontal and temporal regions. The course of the epilepsy was rather benign, with complete control of seizures in four patients and an important reduction in frequency in the remaining three subjects. Other cortical alterations are not usually associated with the typical abnormalities of the posterior fossa in Chiari I malformation; thus, it is possible to hypothesize that cerebral microdysgenesis or, alternatively, a cerebellar dysfunction could underlie epileptogenesis in these patients. |
| | |
Authors:
|
M Elia; R Biondi; V Sofia; S A Musumeci; R Ferri; G Capovilla; P Curatolo |
Related Documents
:
|
17530577 - Stroke-related seizures and epilepsy. 9513857 - Central nervous system complications after lung transplantation. 15668047 - Relationship between severity of epilepsy and developmental outcome in angelman syndrome. 7531487 - Vinorelbine: an active drug for the management of patients with heavily pretreated hodg... 8273977 - The anatomy of appendicitis. 21569107 - Association between the leptin gene 2548g/a polymorphism, the plasma leptin and the met... |
Publication Detail:
|
Type: Case Reports; Journal Article; Multicenter Study |
Journal Detail:
|
Title: Journal of child neurology Volume: 14 ISSN: 0883-0738 ISO Abbreviation: J. Child Neurol. Publication Date: 1999 Jul |
Date Detail:
|
Created Date: 1999-12-09 Completed Date: 1999-12-09 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8606714 Medline TA: J Child Neurol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 446-50 Citation Subset: IM |
Affiliation:
|
Department of Neurology, OASI Institute for Research on Mental Retardation and Brain Aging, Troina, Italy. melia@oasi.en.it |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Arnold-Chiari Malformation / complications, pathology*, physiopathology* Cerebellum / physiopathology Child Electroencephalography* Epilepsy, Complex Partial / etiology*, physiopathology* Female Frontal Lobe / pathology, physiopathology Humans Magnetic Resonance Imaging Male Temporal Lobe / pathology, physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Patterns of pregnancy loss, perinatal mortality, and postneonatal childhood deaths in families of gi...
Next Document: Ischemic stroke and migraine in childhood: coincidence or causal relation?