| Seizure-associated abnormalities in epilepsy: evidence from MR imaging. | |
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MedLine Citation:
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PMID: 15857444 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute seizure-associated changes have been described in the animal and human literature. Controversy exists over whether seizures cause permanent damage to the brain, and whether a (prolonged) seizure can induce changes that lead to an epileptic lesion, resulting in habitual seizures and epilepsy. Current magnetic resonance imaging (MRI) offers a variety of imaging tools and is capable of detecting acute seizure-associated changes. In contrast to the histologic examination, serial MRI studies are possible and allow longitudinal observation of the fate of these changes. This report reviews the literature on acute seizure-associated effects emphasizing the MRI evidence. |
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Authors:
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Regula S Briellmann; R Mark Wellard; Graeme D Jackson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Epilepsia Volume: 46 ISSN: 0013-9580 ISO Abbreviation: Epilepsia Publication Date: 2005 May |
Date Detail:
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Created Date: 2005-04-28 Completed Date: 2005-06-01 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2983306R Medline TA: Epilepsia Country: United States |
Other Details:
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Languages: eng Pagination: 760-6 Citation Subset: IM |
Affiliation:
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Brain Research Institute, Austin and Repatriation Medical Centre, Victoria, Australia. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aspartic Acid / analogs & derivatives*, metabolism Atrophy / pathology Brain / pathology* Brain Diseases / diagnosis, metabolism, pathology Brain Edema / diagnosis, metabolism, pathology Choline / metabolism Creatine / metabolism Diffusion Magnetic Resonance Imaging / statistics & numerical data Epilepsy / diagnosis, metabolism, pathology* Female Hippocampus / pathology Humans Inositol / metabolism Magnetic Resonance Imaging / statistics & numerical data* Magnetic Resonance Spectroscopy / statistics & numerical data Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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56-84-8/Aspartic Acid; 57-00-1/Creatine; 62-49-7/Choline; 6917-35-7/Inositol; 997-55-7/N-acetylaspartate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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