Document Detail

Seizure as a manifestation of intracranial hypotension in a shunted patient.
MedLine Citation:
PMID:  16636618     Owner:  NLM     Status:  MEDLINE    
The authors describe a child with a ventriculo-peritoneal shunt in place for 5 years who presented with 'postural' seizures (seizures on sitting upright, which resolved on recumbency). On shunt tap, the cerebrospinal fluid was obtained freely, but required gentle aspiration with a syringe in the recumbent position, suggesting very low intracranial pressure. Contrast magnetic resonance imaging showed pachymeningeal enhancement and enlargement of the pituitary gland diagnostic of intracranial hypotension along with well-decompressed ventricles. At the time of revision of the shunt, no evidence of malfunction was found and the valve was changed to one with a higher opening pressure. Following this, she became asymptomatic and seizure free. This case illustrates the fact that following shunting, intracranial hypotension may also predispose to seizures, and should be kept in mind while managing these patients.
Deepak Agrawal; Felix A Durity
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric neurosurgery     Volume:  42     ISSN:  1016-2291     ISO Abbreviation:  Pediatr Neurosurg     Publication Date:  2006  
Date Detail:
Created Date:  2006-04-25     Completed Date:  2006-10-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114967     Medline TA:  Pediatr Neurosurg     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  165-7     Citation Subset:  IM    
Copyright Information:
Copyright 2006 S. Karger AG, Basel
Division of Pediatric Neurosurgery, Department of Surgery, University of British Columbia, Vancouver, Canada.
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MeSH Terms
Brain / pathology
Cerebral Ventricles / pathology
Cerebrospinal Fluid Pressure / physiology
Child, Preschool
Equipment Failure Analysis
Hydrocephalus / surgery*
Intracranial Hypotension / etiology*
Magnetic Resonance Imaging
Meninges / pathology
Postoperative Complications / etiology*
Seizures / etiology*
Toxoplasmosis, Congenital / complications
Ventriculoperitoneal Shunt* / instrumentation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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