Document Detail

Segmental radiofrequency ablation of pulmonary vein ostia for patients with refractory paroxysmal atrial fibrillation using multi-slice spiral computed tomography guidance.
MedLine Citation:
PMID:  16358371     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the safety and clinical efficacy of segmental radiofrequency ablation of pulmonary vein (PV) ostia for patients with refractory paroxysmal atrial fibrillation (AF) under multi-slice spiral computed tomography (MSCT) guidance before the procedure. METHODS: A series of 58 consecutive patients with refractory paroxysmal AF were enrolled to undergo segmental radiofrequency ablation of PV ostia. The 36 male and 22 female patients with mean age of (57.4+/-9.5) (32-79) years and no obvious organic heart disease. Before ablation, patients received MSCT to generate 3-dimensional image of the left atrium (LA) and proximal PVs. Patients then underwent segmental radiofrequency ablation of PV ostia using PV circular mapping catheter manipulated several times to ensure complete isolation between PVs and LA. RESULTS: No complications occurred during the procedure. One patient developed delayed cardiac tamponade, which was drained percutaneously. The mean follow-up time was (17.1+/-9.3) months. Forty-one patients (95%) experienced improved quality of life one month after the procedure. Thirty-six patients (83%) showed stable sinus rhythm, while 10 patients (23%) required additional anti-arrhythmic drugs. AF returned> or =1 time in 6 (14%) patients who underwent anti-arrhythmic drug therapy, but the number of episodes was less than that before the procedure. However, one patient experienced recurrent episodes of atrial flutter. CONCLUSION: It is safe and effective to perform segmental radiofrequency ablation of PV ostia for patients with refractory paroxysmal AF using MSCT guidance mappening.
Chen-yang Jiang; Jian-an Wang; Hong He; Yong Sun; Bin-quan Zhou
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of Zhejiang University. Science. B     Volume:  6     ISSN:  1673-1581     ISO Abbreviation:  -     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-16     Completed Date:  2006-01-19     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  101236535     Medline TA:  J Zhejiang Univ Sci B     Country:  China    
Other Details:
Languages:  eng     Pagination:  1153-6     Citation Subset:  IM    
Department of Cardiology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Atrial Fibrillation / radiography*,  surgery*
Catheter Ablation / adverse effects,  methods*
Middle Aged
Pulmonary Veins / radiography*,  surgery*
Risk Assessment
Surgery, Computer-Assisted / methods*
Tomography, Spiral Computed / methods*
Treatment Failure
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Determination of theophylline concentration in serum by chemiluminescent immunoassay.
Next Document:  Validation of the use of foreign gas rebreathing method for non-invasive determination of cardiac ou...