Document Detail


Segmental neurovascular syndromes in children.
MedLine Citation:
PMID:  17645974     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The concept of segmental vascular syndromes with different, seemingly unrelated, diseases is based on the embryology of the neural crest and the mesoderm migration of cells that share the same metameric origin. Migrating patterns of these cells link the brain, the cranial bones, and the face on the same side. A somatic mutation developing in the region of the neural crest or the adjacent cephalic mesoderm before migration can, therefore, be postulated to produce arterial or venous metameric syndromes, including PHACES, CAMS, Cobb syndrome, and Sturge-Weber syndrome. Although these diseases may be rare, their relationships among each other and their postulated linkage with the development of the neural crest and the cephalic mesoderm may shed light on the complex pathology and etiology of various cerebral vascular disorders.
Authors:
T Krings; S Geibprasert; C B Luo; J J Bhattacharya; H Alvarez; Pierre Lasjaunias
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neuroimaging clinics of North America     Volume:  17     ISSN:  1052-5149     ISO Abbreviation:  Neuroimaging Clin. N. Am.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-07-24     Completed Date:  2007-10-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211377     Medline TA:  Neuroimaging Clin N Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  245-58     Citation Subset:  IM    
Affiliation:
Service de Neuroradiologie Diagnostique et Thérapeutique, Hôpital Bicêtre, 78 rue du Général Leclerc, 94275 Le Kremlin-Bicêtre, Paris, France. tkrings@izkf.rwth-aachen.de
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MeSH Terms
Descriptor/Qualifier:
Arteriovenous Malformations*
Brain / abnormalities,  blood supply*
Child
Child, Preschool
Eye Abnormalities*
Face / abnormalities,  blood supply*
Female
Heart Defects, Congenital*
Humans
Intracranial Arteriovenous Malformations
Male
Neural Crest / abnormalities,  blood supply
Spinal Cord / abnormalities,  blood supply*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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