Document Detail

Segmental mediolytic arteritis [correction of arteries]: a case report with review of the literature.
MedLine Citation:
PMID:  9793965     Owner:  NLM     Status:  MEDLINE    
Segmental mediolytic arteritis is a very rare vascular disease which causes sudden intraabdominal hemorrhage. The disease is characterized by degeneration of the arterial media, followed by aneurysmal dilatation and rupture of the involved artery. Up to now, only 13 cases have been reported, and this unique disease is not fully recognized among general pathologists and physicians. Here, we present a case of segmental mediolytic arteritis involving the propria hepatic artery, which resulted in intraabdominal hemorrhage, and consequently hypovolemic circulatory disturbance. Histologically, the rupture focus showed degeneration and desquamation of the intima and media with fibrin-like material covering the exposed adventitia. Inflammatory infiltrates were only noted in the rupture focus as a secondary reactive change. Other than the rupture focus, there were two foci showing similar findings. This disease has rarely been reported and is seldom recognized as a cause of arterial rupture. In cases of sudden intraabdominal hemorrhage, segmental mediolytic arteritis should be considered as a possible cause in addition to atherosclerotic and mycotic aneurysm, traumatic injury and vasculitis syndromes.
Y Nagashima; A Taki; K Misugi; I Aoki; I Tamura; F Fukano; S Suzuki; A Takimoto; Y Inayama; Y Nakatani
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Pathology, research and practice     Volume:  194     ISSN:  0344-0338     ISO Abbreviation:  Pathol. Res. Pract.     Publication Date:  1998  
Date Detail:
Created Date:  1999-01-07     Completed Date:  1999-01-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806109     Medline TA:  Pathol Res Pract     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  643-7     Citation Subset:  IM    
Department of Pathology, Yokohama City University School of Medicine, Japan.
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MeSH Terms
Aneurysm, Ruptured / complications,  pathology*
Arteritis / complications,  pathology*
Hemorrhage / etiology,  pathology
Tunica Media / pathology*
Erratum In:
Pathol Res Pract 1999;195(1):38

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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