| Segmental blood flow through intramyocardial coronary arteries during ventricular systole. | |
| | |
MedLine Citation:
|
PMID: 7877525 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The presented hypothesis assumes, in contrast with the currently prevailing view, that blood continues to flow through the coronary vascular bed even during systole. The contraction of differently oriented myocardial layers closes the penetrating branches of the coronary arteries in the interlayer boundaries. Coronary arteries of a different caliber are during systole under equal intramyocardial pressure. In accordance with the theory of elasticity, the action of an equal external pressure decreases with the lumen of the vessel and, thus, the net effect of these forces will push the blood into smaller vessels within the segment in the layer. This hydrodynamic effect empties the larger coronary arteries during systole so that they are ready for the subsequent massive influx of blood during diastole. The possible applications of this hypothesis in various physiological and pathological conditions are compatible with the present knowledge and might contribute to a more precise understanding of implicated pathophysiological mechanisms. |
| | |
Authors:
|
I Hulín; P Slavkovský |
Related Documents
:
|
2409015 - Histamine and human heart. 16432075 - Physiological basis of clinically used coronary hemodynamic indices. 7377325 - Critical closing and critical opening phenomena in the coronary vasculature of the dog. 2916435 - Comparison of low osmolality ionic (ioxaglate) versus nonionic (iopamidol) contrast med... 8903645 - Seasonal differences in diurnal blood pressure of hypertensive patients living in a sta... 10423075 - Treatment of isolated systolic hypertension in the elderly: the syst-eur trial. systoli... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Medical hypotheses Volume: 43 ISSN: 0306-9877 ISO Abbreviation: Med. Hypotheses Publication Date: 1994 Nov |
Date Detail:
|
Created Date: 1995-04-03 Completed Date: 1995-04-03 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7505668 Medline TA: Med Hypotheses Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 312-4 Citation Subset: IM |
Affiliation:
|
Department of Clinical Pathophysiology of Medical School, Comenius University, Bratislava, Slovakia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Blood Flow Velocity Blood Pressure / physiology Coronary Circulation* Coronary Vessels / physiology* Humans Systole / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A hypothetical mechanism for toxic cataract due to oxidative damage to the lens epithelial membrane.
Next Document: The role of cytokines in early detection of preeclampsia.