Document Detail

Seed migration after transperineal interstitial prostate brachytherapy with I-125 free seeds: analysis of its incidence and risk factors.
MedLine Citation:
PMID:  22798169     Owner:  NLM     Status:  Publisher    
PURPOSE: The purpose of this study was to evaluate the incidence and predictors of seed migration after transperineal interstitial prostate brachytherapy. MATERIALS AND METHODS: From March 2007 to March 2011, 121 patients with stage T1-T2 prostate cancer underwent transperineal interstitial prostate brachytherapy. Pre-planning was performed 3 weeks prior to implantation, and the implants were inserted using the standard parallel needle insertion technique. All patients underwent a series of radiographs [chest radiography, kidney-ureter-bladder (KUB) radiography, and a CT scan] to assess whether seed migration had occurred on postoperative days 1 and 30, and 12 months. RESULTS: Seed migration occurred in 31 (25.6 %) of 121 patients. A total of 51 of 7,883 (0.65 %) implanted seeds migrated. Migration was detected on postoperative day 1 in 16 patients, day 30 in 13 patients and at 12 months in 4 patients (migration occurred at different times in 2 patients). The migrated seeds were found in the lungs, pelvis, heart, mediastinum, kidney, inguinal canal, liver and sacrum. The number of needles was a statistically significant factor in seed migration. CONCLUSIONS: The seeds migrated to many organs. No decrease in the dose administered to the prostate or adverse effects associated with seed migration were noted.
Katsuhito Miyazawa; Munetaka Matoba; Hiroshi Minato; Nobuyo Morita; Ippei Chikazawa; Kiyotaka Ota; Kosuke Tokunaga; Hisao Tonami; Takayuki Nojima; Koji Suzuki
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-14
Journal Detail:
Title:  Japanese journal of radiology     Volume:  -     ISSN:  1867-108X     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101490689     Medline TA:  Jpn J Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Urology, Kanazawa Medical University, Uchinada, Ishikawa, 920-0293, Japan,
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