| Sedative properties of the decoction of the rhizome of Cyperus articulatus. | |
| | |
MedLine Citation:
|
PMID: 11163936 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The decoction of the rhizome of Cyperus articulatus is empirically used in several African countries in the treatment of a wide variety of human diseases. Studies were conducted in mice in order to determine scientifically the pharmacological properties of this medicinal herb. At the same time, the qualitative chemical characterisation of the total extract showed that C. articulatus contains flavonoids, saponins, tannins, terpenes and sugars. The total extract of the rhizome of C. articulatus does not appear to possess either anaesthetic or paralysing effects. In contrast, spontaneous motor activity is significantly reduced by the extract. However, when compared to diazepam, C. articulatus does not seem to have muscle relaxant effects. When associated with sodium thiopental or diazepam, the total extract facilitates sleep induction, and increases the total sleep time without any concomitant analgesic effect. These observations suggest that the rhizome of C. articulatus has pharmacological properties similar to those of sedatives. The sedative actions probably explain at least part of the therapeutic efficiency claimed for this plant in traditional medicine. |
| | |
Authors:
|
V S Rakotonirina; E N Bum; A Rakotonirina; M Bopelet |
Related Documents
:
|
23040676 - Career breaks and changes of sector: challenges for the revalidation of pharmacists. 19574756 - An ayurvedic approach to postpartum depression. 11640086 - The irresistible fascination of medical theories about opposites. 17156416 - Herbal medicine: women's views, knowledge and interaction with doctors: a qualitative s... 8866996 - Presbyopia. 17411576 - Retirement savings plans for radiologists, part 2: a comparison of academic and private... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Fitoterapia Volume: 72 ISSN: 0367-326X ISO Abbreviation: Fitoterapia Publication Date: 2001 Jan |
Date Detail:
|
Created Date: 2001-02-22 Completed Date: 2001-05-24 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 16930290R Medline TA: Fitoterapia Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 22-9 Citation Subset: IM |
Affiliation:
|
Laboratory of Animal Physiology, Faculty of Sciences, University of Yaoundé I, B.P. 812 Yaoundé, Cameroon |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Female Humans Hypnotics and Sedatives / pharmacology* Male Medicine, African Traditional Mice Motor Activity / drug effects* Muscle Relaxation / drug effects Pain / prevention & control Plant Extracts / pharmacology* Plant Roots / chemistry Plants, Medicinal* Sleep / drug effects* |
| Chemical | |
Reg. No./Substance:
|
0/Hypnotics and Sedatives; 0/Plant Extracts |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Anthelmintic activity of crude aqueous extract of Nauclea latifolia stem bark against ovine nematode...
Next Document: A methylflavan with free radical scavenging properties from Pancratium littorale.