Document Detail

Sedation for short hemato-oncologic invasive procedures in children: comparison of propofol-remifentanil and propofol-fentanyl.
MedLine Citation:
PMID:  23412587     Owner:  NLM     Status:  In-Data-Review    
INTRODUCTION: : Short hemato-oncologic procedures are often painful in children, and sedation should be performed outside the operating room.
AIM: : The study aims to compare the effects of remifentanil with those of fentanyl administered during short hemato-oncologic interventions in children.
MATERIALS AND METHODS: : A prospective, randomized study was planned for 29 ASA I to III children (aged, 2 to 18 y) to undergo a total of 60 short oncologic interventions. The patients were placed into 2 groups: propofol-remifentanil (group PR) and propofol-fentanyl (group PF). Group PR was first administered propofol (2 mg/kg) and then remifentanil bolus (0.5 μg/kg). Group PF was first administered propofol (2 mg/kg) and then fentanyl bolus (0.5 μg/kg). Systolic arterial pressure, diastolic arterial pressure, mean arterial pressure, respiratory rate, peripheral oxygen saturation, and heart rate were recorded every 3 minutes during the intervention and every 5 minutes after the operation. Postanesthetic recovery scores, eye-opening time to speech, and recovery time were recorded.
RESULTS: : Comparison of diastolic arterial pressure in groups at minute 3 of the procedure showed significant difference (P<0.05). Eye-opening to speech (P=0.043) and recovery times (P=0.002) were shorter in group PR.
CONCLUSIONS: : During short hemato-oncologic interventions in children, the PR combination is a suitable one for early recovery.
Icten E Ince; Leyla Iyilikci; Sebnem Yilmaz; Dilek Güneş; Muhammed Akkuş; Duyguhan Isguven
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric hematology/oncology     Volume:  35     ISSN:  1536-3678     ISO Abbreviation:  J. Pediatr. Hematol. Oncol.     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-02-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9505928     Medline TA:  J Pediatr Hematol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  112-7     Citation Subset:  IM    
Departments of *Anesthesiology and Intensive Care †Pediatric Hematology ‡Pediatric Oncology, School of Medicine, Dokuz Eylül University, İzmir, Turkey.
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