Document Detail


Sedation administered to very low birth weight premature infants.
MedLine Citation:
PMID:  9134507     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The aim of this study was to evaluate the impact of individualized developmental care for very low birth weight infants on the amount of sedation used in their treatment. STUDY DESIGN: A randomized control trial was conducted. Each infant in the experimental group underwent evaluation weekly, and individualized behaviorally oriented care plans, aimed at reducing stress and promoting self-regulatory behaviors, were prepared and implemented. Control infants received the usual standard of nursery care. Total doses of opioids and chloral hydrate were calculated. Severity of illness during the initial hospital stay was stratified with use of the Neonatal Medical Index. RESULTS: Severely ill infants in the treatment group required less chloral hydrate than those in the control group. Infants who were not severely ill received little or no sedation, and among this subgroup treatment and control infants did not differ. CONCLUSIONS: We speculate that developmentally based care reduces stress levels in severely ill very low birth weight infants and thus decreases sedation requirements.
Authors:
C Heller; J C Constantinou; K VandenBerg; W Benitz; B E Fleisher
Related Documents :
1986597 - Association between hypothermia and mortality rate of premature infants--revisited.
5171687 - Protein intake and plasma amino-acids of infants of low birth weight.
1404527 - Quantitative measurement of muscle and subcutaneous fat thickness in newborn by real-ti...
17908737 - Postdischarge infant mortality among very low birth weight infants: a population-based ...
3734287 - Outcome of pregnancy in women requiring corticosteroids for severe asthma.
2403087 - Hemorrhagic shock and encephalopathy. clinical definition of a catastrophic syndrome in...
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  17     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:    1997 Mar-Apr
Date Detail:
Created Date:  1997-07-16     Completed Date:  1997-07-16     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  107-12     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Stanford University School of Medicine, CA 94305-5119, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Chloral Hydrate / administration & dosage*
Conscious Sedation*
Female
Humans
Hypnotics and Sedatives / administration & dosage*
Infant, Newborn
Infant, Premature, Diseases / drug therapy*
Infant, Very Low Birth Weight*
Intensive Care Units, Neonatal
Male
Narcotics / administration & dosage*
Stress, Physiological / prevention & control*
Treatment Outcome
Grant Support
ID/Acronym/Agency:
M01-RR00070/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Hypnotics and Sedatives; 0/Narcotics; 302-17-0/Chloral Hydrate
Comments/Corrections
Comment In:
J Perinatol. 1999 Jan;19(1):80-1   [PMID:  10685210 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Prenatal ritodrine administration and the incidence of respiratory distress syndrome in premature in...
Next Document:  Relative effects of antepartum and intrapartum maternal blood glucose levels on incidence of neonata...