Document Detail


Secretory villous adenomas that cause depletion syndrome.
MedLine Citation:
PMID:  10219936     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Secretory villous adenomas of the colon have been known to cause a depleting syndrome characterized by dehydration, prerenal azotemia, hyponatremia, hypokalemia, metabolic acidosis, obtundation, and, in severe cases, death. We describe 1 case of classic depleting syndrome and review the literature on possible mechanisms. Both cyclic adenosine monophosphate and prostaglandin E2 have been implicated as possible secretagogue compounds in the pathogenesis of this syndrome unique to the secretory variant form of villous adenomas. Indomethacin as a prostaglandin inhibitor has been used with apparent benefit in controlling the volume of rectal effluent in patients with secretory villous adenomas.
Authors:
J Older; P Older; J Colker; R Brown
Related Documents :
23139286 - Cardiorenal syndrome: the emerging role of protein-bound uremic toxins.
23641306 - A point mutation in ε-sarcoglycan induces inherited myoclonus dystonia syndrome in a ch...
16175786 - Acute colonic pseudo obstruction (ogilvie's syndrome): case report.
2298376 - Treatment of acute colonic pseudoobstruction (ogilvie's syndrome) with cisapride.
6239816 - Spindle microtubular dysfunction in mothers of down syndrome children.
19627606 - Nosologomania: dsm & karl jaspers' critique of kraepelin.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of internal medicine     Volume:  159     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1999 Apr 
Date Detail:
Created Date:  1999-05-05     Completed Date:  1999-05-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  879-80     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, Berkshire Medical Center, Pittsfield, Massachusetts 01201, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adenoma, Villous / complications,  diagnosis*,  surgery
Adult
Diagnosis, Differential
Diarrhea / etiology*
Humans
Male
Rectal Neoplasms / complications,  diagnosis*,  surgery
Syndrome
Water-Electrolyte Imbalance / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Diabetic gustatory sweating successfully treated with topical glycopyrrolate: report of a case and r...
Next Document:  Children's recall of medical experiences: the impact of stress.