Document Detail


Secretory, endoscopic and histopathologic changes and prevalence of Helicobacter pylori in the gastroduodenal mucosa in patients with chronic alcoholic pancreatitis.
MedLine Citation:
PMID:  9216094     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aiming at establishing the prevalence of peptic ulcer in chronic alcoholic pancreatitis and an eventual correlation with gastric acid secretion and endoscopic and histopathologic alterations as well as the presence of Helicobacter pylori in the gastroduodenal mucosa, thirty patients with chronic alcoholic pancreatitis (Group I) and ten control subjects (Group II) were prospectively studied. After upper gastrointestinal endoscopy was performed. Group I was subdivided according to the lack (Subgroup Ia) or a presence (Subgroup Ib) of peptic ulcer. The prevalence of peptic ulcer in these patients was 23.33% clearly higher than that reported in the general population. Baseline and stimulated acid secretion as well as baseline gastrinemia among the subgroups and groups were similar. There was no statistically significant difference in the other parameters evaluated. Due to the increased prevalence of asymptomatic peptic ulcer in patients with chronic alcoholic pancreatitis. Upper gastrointestinal endoscopy is suggested as a diagnosis routine and follow-up of this group of patients.
Authors:
S B André; D R Guarita; C B Mott; R Leitão; A A Laudanna
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Revista do Hospital das Clínicas     Volume:  51     ISSN:  0041-8781     ISO Abbreviation:  Rev Hosp Clin Fac Med Sao Paulo     Publication Date:    1996 Sep-Oct
Date Detail:
Created Date:  1997-10-09     Completed Date:  1997-10-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0415246     Medline TA:  Rev Hosp Clin Fac Med Sao Paulo     Country:  BRAZIL    
Other Details:
Languages:  eng     Pagination:  175-9     Citation Subset:  IM    
Affiliation:
Department of Gastroenterology, Medical School, University of São Paulo.
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MeSH Terms
Descriptor/Qualifier:
Adult
Endoscopy, Gastrointestinal
Female
Gastric Acid / secretion*
Gastric Mucosa / microbiology,  pathology,  secretion
Helicobacter Infections / microbiology*
Helicobacter pylori / isolation & purification
Humans
Intestinal Mucosa / microbiology,  pathology,  secretion
Male
Middle Aged
Pancreatitis, Alcoholic / complications*,  epidemiology*
Peptic Ulcer / microbiology
Prevalence
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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