Document Detail


Secondhand smoke exposure during pregnancy and infantile neurodevelopment.
MedLine Citation:
PMID:  21397902     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
During prenatal development, the nervous system may be more susceptible to environmental toxicants, such as secondhand smoke. The authors assessed the effects of prenatal and postnatal secondhand smoke exposure on the neurodevelopment of 6-month infants. The subjects were 414 mother and infant pairs with no medical problems, taken from the Mothers' and Children's Environmental Health study. Prenatal and postnatal exposures to secondhand smoke were determined using maternal self-reports. Examiners, unaware of exposure history, assessed the infants at 6 months of age using the Bayley Scales of Infant Development. Bayley scores were compared for secondhand smoke exposed and unexposed groups after adjusting for potential confounders. Multiple logistic regression analysis was carried out to estimate the risk of developmental delay posed by SHS exposure. The multivariate model included residential area, maternal age, pre-pregnancy body mass index, education, income, infant sex, parity, birth weight, and type of feeding. After adjusting for covariates, secondhand smoke exposure during pregnancy was found to be related to a decrease in mental developmental index score, but not to a decrease in psychomotor developmental index score. In addition, secondhand smoke exposure during pregnancy was found to increase the risk of developmental delay (mental developmental index score ≤85) at 6 months. This study suggests that the infants of non-smoking women exposed to secondhand smoke are at risk of neurodevelopmental delay.
Authors:
Bo-Eun Lee; Yun-Chul Hong; Hyesook Park; Mina Ha; Ja Hyeong Kim; Namsoo Chang; Young-Man Roh; Boong-Nyun Kim; Yeni Kim; Se-young Oh; Young Ju Kim; Eun-Hee Ha
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-03-12
Journal Detail:
Title:  Environmental research     Volume:  111     ISSN:  1096-0953     ISO Abbreviation:  Environ. Res.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-04-25     Completed Date:  2011-06-22     Revised Date:  2011-12-14    
Medline Journal Info:
Nlm Unique ID:  0147621     Medline TA:  Environ Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  539-44     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Department of Preventive Medicine and Medical Research Institute, School of Medicine, Ewha Womans University, 911-1 Mok-6-Dong, Yangcheon-Gu, Seoul, Republic of Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Air Pollutants / toxicity*
Female
Humans
Infant
Inhalation Exposure / statistics & numerical data
Logistic Models
Male
Maternal Exposure / statistics & numerical data*
Nervous System / drug effects*,  growth & development
Pregnancy
Prenatal Exposure Delayed Effects / epidemiology*
Tobacco Smoke Pollution / statistics & numerical data*
Chemical
Reg. No./Substance:
0/Air Pollutants; 0/Tobacco Smoke Pollution
Comments/Corrections
Comment In:
Environ Res. 2011 Nov;111(8):1332-3   [PMID:  21996059 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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