| Secondary systemic lupus erythematosus: an analysis of 4 cases of uncontrolled hereditary angioedema. | |
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MedLine Citation:
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PMID: 17098477 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The association of systemic lupus erythematosus and hereditary angioedema (HAE) has formed the basis of numerous case reports and is hypothesised to result from consumption of complement C4 with consequent impaired clearance of apoptotic cells. We describe the development of frank lupus or lupus-like syndrome in four HAE patients with uncontrolled angioedema and low levels of serum C4. Measures that limit hypocomplementaemia in HAE may reduce the incidence of secondary SLE. |
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Authors:
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Sujoy Khan; Michael D Tarzi; Philip C Doré; W A C Sewell; Hilary J Longhurst |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2006-11-13 |
Journal Detail:
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Title: Clinical immunology (Orlando, Fla.) Volume: 123 ISSN: 1521-6616 ISO Abbreviation: Clin. Immunol. Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-03-19 Completed Date: 2007-05-04 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100883537 Medline TA: Clin Immunol Country: United States |
Other Details:
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Languages: eng Pagination: 14-7 Citation Subset: IM |
Affiliation:
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Path Links Immunology, Scunthorpe General Hospital, Scunthorpe, North Lincolnshire, UK. Sujoy.khan@nlg.nhs.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Angioedema / complications*, immunology*, physiopathology Complement C4 / deficiency* Female Humans Lupus Erythematosus, Systemic / complications*, immunology*, physiopathology Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Complement C4 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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