Document Detail

Secondary sclerosing cholangitis and portal hypertension after O157 enterocolitis: Extremely rare complications of hemolytic uremic syndrome.
MedLine Citation:
PMID:  11733919     Owner:  NLM     Status:  MEDLINE    
The authors experienced an extremely rare case of secondary sclerosing cholangitis and portal hypertension developed as late complications of hemolytic uremic syndrome (HUS) owing to Escherichia coli O157:H7 in a 2-year-old boy. HUS after E coli O157 infection is the most frequent cause of acute renal failure in childhood and occasionally is accompanied by extrarenal complications such as encephalopathy, cardiomyopathy, ischemic colitis, and pancreatitis. Rarely, late colonic stenosis may develop secondary to the ischemic damage. Sclerosing cholangitis and subsequent cirrhosis with portal hypertension are very uncommon as late complications of HUS. To our knowledge, such a case has not been previously reported in the literature. J Pediatr Surg 36:1838-1840.
N Urushihara; N Ariki; T Oyama; Y Chouda; T Yagi; T Inoue; Y Tomiyama; R Nishiuchi; M Oda; N Tanaka
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  36     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2001 Dec 
Date Detail:
Created Date:  2001-12-04     Completed Date:  2002-04-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1838-40     Citation Subset:  IM    
Copyright Information:
Copyright 2001 by W.B. Saunders Company.
Department of Surgery, Okayama University Medical School, Okayama, Japan.
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MeSH Terms
Child, Preschool
Cholangitis, Sclerosing / etiology*
Enterocolitis / complications*
Escherichia coli Infections / complications*
Escherichia coli O157 / chemistry
Hemolytic-Uremic Syndrome / complications*
Hypertension, Portal / etiology*
Shiga Toxins / adverse effects
Reg. No./Substance:
0/Shiga Toxins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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