| Secondary prevention after myocardial infarction: effects of beta blocking agents and calcium antagonists. | |
| | |
MedLine Citation:
|
PMID: 2908719 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Therapeutic interventions in patients with myocardial infarction, whether during the first hours after coronary occlusion or several days later, aim to reduce mortality and morbidity by several mechanisms: Prevention of fatal ventricular fibrillation, limitation of infarct size, and inhibition of platelet aggregation are some examples of such mechanisms. Results from early intervention trials with beta blocking agents, particularly from ISIS-I, suggest that 1-year mortality is significantly lower in selected patients randomized to active treatment. Late intervention studies also suggest a significant reduction in coronary mortality and morbidity with beta blockade, particularly when data are pooled. Studies with the calcium channel blockers nifedipine and verapamil were unable to demonstrate any beneficial effects of these drugs on mortality or reinfarction. In this review article, attention will be directed to the most recent information about the preventive value of beta adrenergic blocking drugs and slow calcium channel inhibitors. |
| | |
Authors:
|
P Depelchin; J Sobolski; M Jottrand; C Flament |
Related Documents
:
|
22280429 - Diastolic heart failure and lv dyssynchrony. 21972399 - Detection of lipid-core plaques by intracoronary near-infrared spectroscopy identifies ... 22511369 - Complete interventional heart repair of multiple concomitant cardiac pathologies in a s... 21713529 - Evaluation of left ventricular twist in acute myocardial infarction patients using spec... 22513959 - Preoperative statin therapy for patients undergoing cardiac surgery. 22360839 - The mechanics of left ventricular dysfunction in patients with churg-strauss syndrome. 22280429 - Diastolic heart failure and lv dyssynchrony. 15659949 - Noninvasive ventilation for acute respiratory failure. 20189069 - Myocardial bridging on dual-source computed tomography: degree of systolic compression ... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy Volume: 2 ISSN: 0920-3206 ISO Abbreviation: Cardiovasc Drugs Ther Publication Date: 1988 May |
Date Detail:
|
Created Date: 1991-04-26 Completed Date: 1991-04-26 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 8712220 Medline TA: Cardiovasc Drugs Ther Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 139-48 Citation Subset: IM |
Affiliation:
|
Medical Cardiology Services Hôpital Académique Erasme Université Libre de Bruxelles Belgium. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenergic beta-Antagonists
/
therapeutic use* Calcium Channel Blockers / therapeutic use* Humans Myocardial Infarction / prevention & control* Recurrence |
| Chemical | |
Reg. No./Substance:
|
0/Adrenergic beta-Antagonists; 0/Calcium Channel Blockers |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: According to MIAMI and ISIS-I trials, can a general recommendation be given for beta blockers in acu...
Next Document: Hemodynamic effects of celiprolol at rest and during exercise; a comparison with enalapril.