| Secondary polycythemia associated with idiopathic membranous nephropathy. | |
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MedLine Citation:
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PMID: 10970991 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 58-year-old male patient had secondary polycythemia associated with idiopathic nephrotic syndrome. The renal biopsy revealed membranous nephropathy, and the bone marrow biopsy disclosed hypercellular marrow with mild panhyperplasia. The concentration of serum erythropoietin was 8.5 mU/ml. The erythrocytosis was characterized by an increased red cell volume (40.2 ml/kg) and normal arterial oxygen saturation. There were no associated lesions that could induce secondary polycythemia, except the biopsy-proven membranous nephropathy. He was treated with prednisolone and cyclophosphamide, and the nephrotic syndrome was partially remitted after 6 weeks. With partial remission of nephrotic syndrome, the erythrocytosis was resolved. This case illustrates the rarely reported association of the nephrotic syndrome and erythrocytosis, and the resolution of erythrocytosis with improvement of nephrotic syndrome. |
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Authors:
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C S Lim; K H Jung; Y S Kim; C Ahn; J S Han; S Kim; J S Lee |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: American journal of nephrology Volume: 20 ISSN: 0250-8095 ISO Abbreviation: Am. J. Nephrol. Publication Date: 2000 Jul-Aug |
Date Detail:
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Created Date: 2000-10-10 Completed Date: 2000-11-07 Revised Date: 2007-02-14 |
Medline Journal Info:
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Nlm Unique ID: 8109361 Medline TA: Am J Nephrol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 344-6 Citation Subset: IM |
Copyright Information:
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Copyright 2000 S. Karger AG, Basel |
Affiliation:
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Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bone Marrow
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pathology Cyclophosphamide / therapeutic use Drug Therapy, Combination Erythrocyte Volume Erythropoietin / blood Glomerulonephritis, Membranous / complications*, drug therapy, pathology Glucocorticoids / therapeutic use Humans Hyperplasia Male Microscopy, Electron Middle Aged Nephrotic Syndrome / complications, drug therapy Oxygen / blood Polycythemia / etiology*, pathology Prednisolone / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Glucocorticoids; 11096-26-7/Erythropoietin; 50-18-0/Cyclophosphamide; 50-24-8/Prednisolone; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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