Document Detail

Secondary hemicrania continua: Case reports and a literature review.
MedLine Citation:
PMID:  19215945     Owner:  NLM     Status:  MEDLINE    
Hemicrania continua (HC) is an indomethacin responsive primary headache disorder. Secondary or symptomatic HC is associated with another neurological or non-neurological disease. We report three patients with secondary HC. We also review the literature to identify the clinical predictors of an underlying disease entity. Intracranial structural lesion, head and neck vessel pathology, and carcinoma lung should be suspected in every patient. The factors that may suggest a secondary pathology are: elderly age, male sex, smoking habit, constitutional symptoms, symptoms related to respiratory system, frequent and short-lived exacerbation, nocturnal exacerbation, HC evolving from remitting form, recent neck and/or head trauma, miosis, elevated ESR, and fading effect of indomethacin. We recommend MRI brain in all the patients presenting with HC or HC like headache. Angiography and CT chest are two other investigations that may be supplemented in patients with high risk for head/neck vessel pathology and carcinoma lung.
Sanjay Prakash; Nilima D Shah; Ritu Kanchan Soni
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-02-12
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  280     ISSN:  1878-5883     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-06     Completed Date:  2009-08-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  29-34     Citation Subset:  IM    
Department of Neurology, Medical College, Baroda, Gujarat 390001, India.
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MeSH Terms
Age Factors
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Blood Sedimentation
Brain / pathology
Craniocerebral Trauma / complications
Diagnosis, Differential
Headache Disorders, Secondary / diagnosis*,  drug therapy,  physiopathology*
Indomethacin / therapeutic use
Middle Aged
Miosis / complications
Risk Factors
Sex Factors
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 53-86-1/Indomethacin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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