Document Detail

Secondary amyloidosis causing nephrotic syndrome in a patient with non-Hodgkin's lymphoma: quite a rare diagnosis.
MedLine Citation:
PMID:  16898966     Owner:  NLM     Status:  MEDLINE    
Secondary amyloidosis is usually a complication of chronic inflammation. Amyloidosis cases during the course of non-Hodgkin's lymphoma (NHL) are usually of AL-type, only one NHL patient with secondary amyloidosis has been reported. Our 79-year-old male patient visited us with multiple lymphadenopathies, and he was diagnosed with nodal marginal zone B-cell lymphoma. After four cycles of combined chemotherapy; his urea, creatinine levels started to increase and he developed nephrotic-range proteinuria. His rectal biopsy demonstrated amyloid deposition in submucosal vessel walls. The patient has been under hemodialysis for 10 months and his lymphoma is still in partial remission. We presented this case because it is the second NHL patient who developed secondary amyloidosis during his disease course.
G E Pamuk; M Demir; H Orüm; B Turgut; F Ozyilmaz; E Tekgündüz
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical and laboratory haematology     Volume:  28     ISSN:  0141-9854     ISO Abbreviation:  Clin Lab Haematol     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-10     Completed Date:  2006-10-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7907061     Medline TA:  Clin Lab Haematol     Country:  England    
Other Details:
Languages:  eng     Pagination:  259-61     Citation Subset:  IM    
Division of Hematology, Trakya University Medical Faculty, Edirne, Turkey.
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MeSH Terms
Amyloidosis / etiology*
Lymphoma, B-Cell / complications*,  drug therapy
Nephrotic Syndrome / diagnosis,  etiology*

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